Evaluation of Some Cardiac Functions among Children with Vitamin D Deficiency Rickets

Kotb A Metwalley, Duaa M Raafat* and Asmaa F Hassan

Vitamin D deficiency rickets (VDDR) is commonly recognised disease in Egypt. The most striking  biochemical fi nding in this illness is hypocalcaemia which may affect ventricular contraction. This study was a prospective hospital based study aiming to evaluate some cardiac functions among children with VDDR by Echocardiography.

Patients and Methods: Patients: The included 100 patients (Group 1) with VDDR in addition to control group (Group 2) which included 50 healthy children. Methods: all cases were subjected to a thorough history, full clinical examinations and investigations which include: serum calcium, phosphorus, alkaline phosphatase, 25(OH) vitamin D, parthhormone, chest x ray, electrocardiogram and echocardiography to measure [left ventricular functions systolic function which include( ejection fraction% (EF%), fraction shortening% (FS%) left ventricular end diastolic diameter(LVEDD) and left ventricular end systolic diameter (LVESD)] .

Results: EF%&FS% were signifi cantly lower while LVEDD & LVESD were signifi cantly higher among studied VDDR cases (Group 1) when compared with control (Group 2). These echocardiographic parameters were improved with treatment with vitamin D and calcium. Conclusions: children with VDDR have a signifi cant impairment in left ventricle systolic functions which improved with appropriate treatment.

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Published on: Dec 30, 2016 Pages: 7-12

Full Text PDF Full Text HTML DOI: 10.17352/ac.000002
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