Background: To evaluate aerobic capacity and muscle function in patients with Relapsing Polychondritis (RP).
Methods: A cross-sectional single center study evaluated seven women with RP (McAdam criteria) that were compared to seven healthy control individuals matched for age, gender, and body mass index. Both groups performed a treadmill-graded maximal exercise. Aerobic capacity was assessed by peak oxygen uptake (VO2 peak), time at anaerobic Ventilatory Threshold (VAT) and Respiratory Compensation Point (RCP) and time-to-exhaustion. Muscle function was evaluated through the sit-to-stand and the timed up-and-go test.
Results: RP patients had an average age of 52.7 years. Disease was stable with at least one immunosuppressive drug and without glucocorticoid. Patients showed an impaired aerobic capacity characterized by lower VO2 peak (relative and absolute), and lower time-to-exhaustion. Furthermore, patients had also a tendency to impairment in lower extremities muscle function, when compared with control group.
Main findings: In the present study, patients with RP show a tendency to impaired aerobic capacity and lower extremities muscle function when compared with healthy individuals. Further studies should confirm the present findings.
Keywords:
Published on: Apr 7, 2020 Pages: 7-10
Full Text PDF
Full Text HTML
DOI: 10.17352/raoa.000012
CrossMark
Publons
Harvard Library HOLLIS
Search IT
Semantic Scholar
Get Citation
Base Search
Scilit
OAI-PMH
ResearchGate
Academic Microsoft
GrowKudos
Universite de Paris
UW Libraries
SJSU King Library
SJSU King Library
NUS Library
McGill
DET KGL BIBLiOTEK
JCU Discovery
Universidad De Lima
WorldCat
VU on WorldCat
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."