Research Interest: I have expertise in biochemistry, molecular biology, neuro-oncology, and neuroscience. Currently, my most important areas of investigation include neuro-oncology and neurological diseases. I have been conducting research for more than 20 years in different malignant diseases of blood, breast, brain, and adrenal gland. I also conduct molecular studies in neurodegenerative disorders.

Research Interest: Lung and breast translational research, Toward personalized medicine of lung cancer: response to nontargeted therapy in invasive pulmonary adenocarcinoma as a function of tumor cell differentiation, Primary malignant fibrous histiocytoma (myxofibrosarcoma/pleomorphic sarcoma not otherwise specified) of the breast: clinicopathologic study of 19 cases, Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of 20 cases, Del(5q) is associated with clinical and histological parameters in small cell neuroendocrine lung carcinoma., Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series.

Research Interest: Extracellular matrix, glycosaminoglycans, hyaluronan, Inflammation – experimental models, Free radicals – oxidants and antioxidants, NF-kB pathway and cytokines, TLRs and innate immunity.

Research Interest: • Pathophysiology and molecular immunology applied to immunological research lines.• Molecular processes underlying the interaction between receptors of the immune response, inflammation and characterization of new anti-inflammatory molecules. • Novel therapies for Sjögren’s syndrome autoimmune disease. • Evaluation of the pathogenic role of autoantibodies produced in the course of autoimmune diseases. e.t.c,

Research Interest: Microbiology, Infectious diseases, Antimicrobial resistance.

Research Interest: Hybrid molecular imaging (PET/CT and SPECT/CT), oncology (particularly colorectal and head & Neck cancer and malignant lymphoma), criteria of response assessment after therapy (by conventional imaging and molecular imaging) and meta-analysis.

Research Interest: Diagnosing and treating of various hematopathy,especially in multiple myeloma and Pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria. Therapeutic method including comprehensive treatment, drug treatment, immunological treatment and bone marrow transplantation

Research Interest: 1. Primary rat astroglial cells cultures. 2. Neuroblastoma and glioblastoma cells cultures. 3. Effect of antioxidant molecules [(+) thioctic acid, (+/-) thioctic acid] and choline containing compounds on proliferation and differentiation neural cell culture. 4. Study of anticancer molecules (e.g. bortezomib) and neuroprotective ones (e.g. thioctic acid) in in vitro model of neoplastic cell cultures. 5. Effect of alpha lipoic acid and choline-containing compounds, on the expression of some astroglial biomarkers during proliferation and differentiation of astrocyte cell cultures and neuroblastoma cell lines.

Research Interest: My current areas of interest include in vitro fertilization, ICSI, studies of human gamete, zygote and embryo morphology in relation to their developmental ability, and chromosomal constitution (PGD, PGS), as well as the cryopreservation of embryos and oocytes.

Research Interest: Mechanistic toxicology of carcinogenic/neurotoxic substances, occupational/environmental toxicants, & gene therapy for management • Reproductive toxicology with regard to intra-spermatozoal signaling associated to occupational/environmental toxicants.

Research Interest: 1. biologia Geral, 2. Genética, 3. Fisiologia de Órgãos e Sistemas, 4. Ciências Biológicas

I have completed my PhD in Cell Biology, working with glioma cells and studying their behavior, using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and morphology, to study the angiogenesis response of endothelial cells in glioma, and the role of inflammatory mediators. After this, I did a post-doctoral period in Spain, where I worked with artificial skin and stem cells. I did other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer) worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I am an Associated Professor in Histology at Federal University of Santa Catarina- Brazil.

Research Interest: Cancer (Central nervous system and melanoma), angiogenesis, invasion and migration of tumoral cells

List of Publication:

I approached science in 1999-2000 as AFS exchange students in Atlanta GA, USA. I graduated from medical school G. d’Annunzio University, Chieti in 2007, with my research project “Evaluation of E6-E7 proteins in HPV related lesion of the cervix”. In 2008 I started working at Histopathology Dept., ASL2 Lanciano-Vasto-Chieti “SS Annunziata” Hospital, Chieti, Italy and at Histopathology Dept., “G. Bernabeo” Hospital, Ortona (CH), Italy. In 2011 I have got involved in academic activities such as teaching in clinical practice to junior doctors and medical students and I kept working on HPV related lesions and on target therapy in lung cancer.

In 2012 and 2013 I was a visitor fellow at University College London Hospital, London.

On July 2014 I finished my training in Histo/Cytopathology discussing my research project on renal pathology which is still on going. Since August 2014 I am on GMC Specialist Register.

Now I am working as Clinical Fellow in Histopathology at Royal Brompton Hospital, London focusing on cardiothoracic pathology.

Research Interest: Lung cancer, breast cancer, HPV related disease and IgA nephropathy.

Number of Publication: 24

Research Interest: Medicinal plants valorization, Natural compounds’ action mechanism elucidation, Chemical-biology, Tumoral hepatic microenvironment, Infectious diseases.

Research Interest: CNS lymphomas, immunodeficiency associated lymphoproliferative disorders, therapy associated myeloid neoplasms and acute myeloid leukemia.